AS-410M – Auto Slide Preparation System

Automated high-quality, consistent sectioning ideal for digital pathology.

With a capacity of 96 paraffin blocks and 400 slides, the AS-410M can free up resources for other important tasks.

The fully automatic sectioning device is capable of cutting up to 96 paraffin blocks as well as delivering 400 sections mounted on slides, registered, dried and ready for further analysis.

All in just ~ 3 hours – and without the intervention of a user along the way, which gives a crucial capacity boost to the laboratory.

Fewer hands are involved, and far more samples come through the system in less time for the benefit of both clinicians and patients.

Sample Identification Function (BR)

The barcode information printed on the cassette is read and printed on the slide glass to prevent sample mix-ups.

Scans the barcode information printed on the cassette

Prints the read barcode information onto the slides

Checks that the barcode information of the cassette matches the information printed on the slide.

Automatic Orientation Function

After measuring the block surface angle and height, the tilt of the sample holder is automatically adjusted so that the block surface is parallel to the blade.

Temperature Control Function (internal and stretching board)

The temperature inside the system is controlled using a cooler, in order to keep the sectioning environment constant. In addition, the temperature for stretching and drying can be adjusted to ensure optimum results.

Automatic process using a carrier tape

The sections that have been cut, are attached on-the-fly to the tape and are automatically transferred to the slide glass.

Blade Mark Check Function (DB)

The section mounted on the slide is photographed, and if a blade scratch is detected, the position of the blade is changed or it is replaced so that the same doesn’t occur for the rest of the sectioning.

Automatic Blade Replacement Function

The microtome blades are automatically supplied from the dedicated replacement blade cassette, preventing injuries during replacements.

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Technical Specifications

Block capacity	96 blocks
Slide capacity	400 slides
Section thickness	3-10 µm
Block sizes	Recommended block size is 24x24mm, 24x30mm, 23x31mm, 24x37mm The AS-410M can cut smaller blocks, but without the automatic adjustment of the block in relation to the microtome knife. Height of blocks 5-14mm.
Quality options	CCD camera and software for autotrimming. Barcode reader for internal prints. CCD camera and software for quality check knife marks and other artefacts. Function with the option of placing two sections on slides. Expansion package for communication with LIS systems.